U.S. Patents

R.K. Draper,* C.A. Mikoryak, R.-H. Wang and P. Pantano, Method to Measure Carbon Nanotubes Taken-Up by a Plurality of Living Cells, U.S. Patent 8,632,671 (awarded 21 January 2014).

K.J. Balkus, Jr.,* P. Pantano,* C.C. Meek and D.H. Coutinho, Encoded Molecular Sieve Particle-based Sensors, U.S. Patent 6,790,672 (awarded 14 September 2004).

P. Pantano,* S.S. Khan, E.S. Jin and H.W. Stokes, Jr., Thin Film Fiber Optic Electrode Sensor Array and Apparatus for Concurrent Viewing and Chemical Sensing of a Sample, U.S. Patent 6,487,326 (awarded 26 November 2002).

D.R. Walt* and P. Pantano, Superresolution Imaging Fiber for Subwavelength Light Energy Generation and Near-Field Optical Microscopy, U.S. Patent 5,633,972 (awarded 27 May 1997).

Peer-Reviewed Publications

Karimi, S.; Troeung, M.; Wang, R.; Draper, R.K.; Pantano, P.;* Crawford, S. and Aravamudhan, S. Acute and Chronic Toxicity to Daphnia Magna of Colloidal Silica Nanoparticles in a Chemical Mechanical Planarization Slurry after Polishing a GaAs Wafer, NanoImpact 13, 56-65 (2019).

Karimi, S.; Troeung, M.; Wang, R.; Draper, R.K. and Pantano, P.* Acute and Chronic Toxicity of Metal Oxide Nanoparticles in Chemical Mechanical Planarization Slurries with Daphnia Magna, Environmental Science: Nano 5, 1670-1684 (2018).

Wang, R.; Lee, Jr., M.; Kinghorn, K.; Hughes, T.; Chuckaree, I.; Lohray, R.; Chow, E.; Pantano, P. and Draper, R.K.* Quantitation of Cell-associated Carbon Nanotubes: Selective Binding and Accumulation of Carboxylated Carbon Nanotubes by Macrophages, Nanotoxicology 12, 677-698 (2018).

Pantano, P.;* Harrison. C.D.; Poulose, J.; Urrabazo Jr., D.; Norman, T.Q.; Braun, E.I.; Draper, R.K. and Overzet, L.J. Factors Affecting the 13.56-MHz Radio-Frequency Mediated Heating of Gold Nanoparticles, Applied Spectroscopy Reviews 52, 821-836 (2017).

Braun, E.I.; Huang, A.; Tusa, C.A.; Yukica, M.A. and Pantano, P.* Use of Raman Spectroscopy to Identify Carbon Nanotube Contamination at an Analytical Balance Workstation, Journal of Occupational and Environmental Hygiene 13, 915-923 (2016).

Murali, V.S.; Wang, R.; Mikoryak, C.; Pantano, P. and Draper, R.K.* The Impact of Cellular Location on the Near Infrared-Mediated Thermal Ablation of Cells by Targeted Carbon Nanotubes, Nanotechnology 27, 425102 (2016).

Braun, E.I.; Draper, R. and Pantano, P.* Enhanced Surface Acidity for Surfactant-Free Suspensions of Carboxylated Carbon Nanotubes Purified by Centrifugation, Analytical Chemistry Research 8, 26-33 (2016).

Wang, R.; Meredith, A.N.; Lee Jr., M.L.; Detusch, D.; Miadzvedskaya, L.; Braun, E. Pantano, P.; Harper, S. and Draper, R.* Toxicity Assessment and Bioaccumulation in Zebrafish Embryos Exposed to Carbon Nanotubes Suspended in Pluronic® F-108, Nanotoxicology 10, 689-698 (2016).

Murali, V.S.; Wang, R.; Mikoryak, C.A.; Pantano, P. and Draper, R.K.* Rapid Detection of Polyethylene Glycol Sonolysis upon Functionalization of Carbon Nanomaterials, Experimental Biology and Medicine, 240, 1147-1151 (2015).

Speed, D.;* Westerhoff, P.; Sierra-Alvarez, R.; Draper, R.; Pantano, P.; Aravamudhan, S.; Chen, K.L.; Hristovski, K.; Herckes, P.; Bi, X.; Yang, Y.; Zeng, C.; Otero-Gonzalez, L.; Mikoryak, C.; Wilson, B.A.; Kosaraju, K.; Tarannum, M.; Crawford, S.; Yi, P.; Liu, X.; Babu, S.V.; Moinpour, M.; Ranville, J.; Montano, M.; Corredor, C.; Posner, J. and Shadman, F. Physical, Chemical, and In Vitro Toxicological Characterization of Nanoparticles in Chemical Mechanical Planarization Suspensions Used in the Semiconductor Industry: Towards Environmental Health and Safety Assessments, Environmental Science: Nano, 2, 227-244 (2015).

Braun, E.I. and Pantano, P.* The Importance of an Extensive Elemental Analysis of Single-Walled Carbon Nanotube Soot, Carbon 77, 912-919 (2014).

Chilek, J.L.; Wang, R.; Draper, R.K. and Pantano, P.* Use of Gel Electrophoresis and Raman Spectroscopy to Characterize the Effect of the Electronic Structure of Single-Walled Carbon Nanotubes on Cellular Uptake, Analytical Chemistry 86, 2882-2887 (2014).

Bajaj, P.; Mikoryak, C.; Wang, R.; Bushdiecker II, D.K.; Memom, P.; Dieckmann, G.R.; Draper, R.K.; Pantano, P. and Musselman, I.H.* A Carbon Nanotube-based Raman Imaging Immunoassay for Evaluating Tumor Targeting Ligands, Analyst 139, 3069-3076 (2014).

Wang, R.; Hughes, T.; Beck, S.; Vakil, S.; Li, S.; Pantano, P. and Draper, R.K.* Generation of Toxic Degradation Products by Sonication of Pluronic® Dispersants: Implications for Nanotoxicity Testing, Nanotoxicology 7, 1272-1281 (2013).

Pantano, P.;* Draper, R.K.; Mikoryak, C. and Wang, R. Electrophoretic Methods to Quantify Carbon Nanotubes in Biological Cells, in Handbook of Carbon Nano Materials, F. D’Souza and K. M. Kadish, Eds.; World Scientific Publishers, Singapore, Vol. 3, pp. 83-106 (2012).

Sheardy, A.T.; Taylor, J.J.; Chilek, J.L.; Li, S.; Wang, R.; Draper, R.K and Pantano, P.* Study of the Near Infrared Heating of Dispersions of Protein-coated Pristine and Carboxylated Single-Walled Carbon Nanotubes, International Journal of Nanoscience, 11, 1250034 (2012).

Jacobsen, N.J. and Pantano, P.* Determining the Percentages of Semiconducting and Metallic Single-Walled Carbon Nanotubes in Bulk Soot, Carbon 49, 1998-2006 (2011).

Wang, R.; Mikoryak, C.; Li, S.; Bushdiecker II, D.; Musselman, I.H.; Pantano, P. and Draper, R.K.* Cytotoxicity Screening of Single-Walled Carbon Nanotubes: Detection and Removal of Cytotoxic Contaminants from Carboxylated Carbon Nanotubes, Molecular Pharmaceutics 8, 1351-1361 (2011).

Marches, R.; Mikoryak, C.; Wang, R.; Pantano, P.; Draper, R.K. and Vitetta, E.S.* The Importance of Cellular Internalization of Antibody-Targeted Carbon Nanotubes in the Photothermal Ablation of Breast Cancer Cells, Nanotechnology 22, 095101 (2011).

Marches, R.; Chakravarty, P.; Bajaj, P.; Musselman, I.H.; Pantano, P.; Draper, R.K. and Vitetta, E.S.* Specific Thermal Ablation of Tumor Cells using a Monoclonal Antibody Covalently Coupled to a Single-Walled Carbon Nanotube, International Journal of Cancer 125, 2970-2977 (2009).

Katari, S.C.; Wallack, M.; Hubenscmidt, M.; Pantano, P.* and Garner, H.R.* Fabrication and Evaluation of a Near-Infrared Hyperspectral Imaging System, Journal of Microscopy 236, 11-17 (2009).

R. Wang, C. Mikoryak, E. Chen, S. Li, P. Pantano and R.K. Draper,* Gel Electrophoresis Method to Measure the Concentration of Single-Walled Carbon Nanotubes Extracted from Biological Tissue, Analytical Chemistry 81, 2944-2952 (2009).

P. Chakravarty, R. Marches, N.S. Zimmerman, A.D.-E. Swafford, P. Bajaj, I.H. Musselman, P. Pantano, R.K. Draper and E.S. Vitetta,* Thermal Ablation of Tumor Cells with Antibody-Functionalized Single-Walled Carbon Nanotubes, Proceedings of the National Academy of Science, USA 105, 8697-8702 (2008).

H.N. Yehia, R.K. Draper, C. Mikoryak, E.K. Walker, M.C. Daigrepont, I.H. Musselman, P. Bajaj, G.R. Dieckmann and P. Pantano,* Single-Walled Carbon Nanotube Interactions with HeLa Cells, Journal of Nanobiotechnology 5, 8-24 (2007).

K.A. Hartzell, K.L. Danowski and P. Pantano,* Combined Imaging and Chemical Sensing with a Disposable Microscope Objective Chemical Sensor, Applied Spectroscopy Reviews 43, 1-21 (2007).

S.-F. Chin, R.H. Baughman, A.B. Dalton, G.R. Dieckmann, R.K. Draper, C. Mikoryak, I.H. Musselman, V.Z. Poenitzsch, H. Xie and P. Pantano,* Amphiphilic Helical Peptide Enhances the Uptake of Single-Walled Carbon Nanotubes by Living Cells, Experimental Biology and Medicine 232, 1236-1244 (2007).

S.-F. Chin and P Pantano,* Antibody-Modified Microwell Arrays and Photobiotin Patterning on Hydrocarbon-Free Glass, Microchemical Journal 84, 1-9 (2006).

P. Zhao, Y. Zhao, A. D. Sherry* and P. Pantano,* Concurrent 31P Nuclear Magnetic Resonance Spectroscopy and Fiber-Optic Oxygen Consumption Measurements in Perfused Rat Hearst, Methods in Enzymology 381, 735-746 (2004).

S.E. Carranza and P. Pantano,* Fluorescence Microscopy and Flow Cytofluorometry of Reactive Oxygen Species, Applied Spectroscopy Reviews 38, 245-261 (2003).

C.C. Meek, D. H. Coutinho, K. J. Balkus, Jr.* and P. Pantano,* Optical Encoding of Microwell Arrays with Molecular Sieve Particles, Lab on a Chip 3, 132-135 (2003).

S.-K. Quah, K.L. Danowski and P. Pantano,* Microwell Array Photoimprint Lithography: Micropost Sensors and Guidance of Neuronal Processes, Biomedical Microdevices 4, 123-130 (2002).

C.C. Meek and P. Pantano,* Spatial Confinement of Avidin Domans in Microwell Arrays, Lab on a Chip 1, 158-163 (2001).

E.S. Jin, B.J. Norris and P. Pantano,* An Electrogenerated Chemiluminescence Imaging Fiber Electrode Chemical Sensor for NADH, Electroanalysis 13, 1287-1290 (2001).

K.L. Danowski and P. Pantano,* Evaluating the Chemical Spatial Resolution of Imaging Fiber Chemical Sensors, Microchemical Journal 70, 51-61 (2001).

D.D. Bernhard, S. Mall and P. Pantano,* Fabrication and Characterization of Microwell Array Chemical Sensors, Analytical Chemistry 73, 2484-2490 (2001).

Y.-H. Liu, T.H. Dam and P. Pantano,* A pH-Sensitive Nanotip Array Imaging Sensor, Analytica Chimica Acta 419, 215-225 (2000).

S.S. Khan, E.S. Jin, N. Sojic and P. Pantano,* A Fluorescence-Based Imaging Fiber Electrode Chemical Sensor for Hydrogen Peroxide, Analytica Chimica Acta 404, 213-221 (2000).

T.H. Dam and P. Pantano,* Nanotip Array Photoimprint Lithography, Review of Scientific Instrumentation 70, 3982-3986 (1999).

Y. Zhao, A. Richman, C. Storey, N.B. Radford and P. Pantano,* In Situ Fiber-Optic Oxygen Consumption Measurements from a Working Mouse Heart, Analytical Chemistry 71, 3887-3893 (1999).

K.L. Michael, J.A. Ferguson, B.G. Healey, A.P. Panova, P. Pantano and D.R. Walt,* The Use of Optical Imaging Fibers for the Fabrication of Array Sensors, American Chemical Society Symposium Series, 690; Chapter 23; 273-289 (1998).

A.P. Panova, P. Pantano and D.R. Walt,* In Situ Fluorescence Imaging of Localized Corrosion with a pH-sensitive Optical Imaging Fiber, Analytical Chemistry 69, 1635-1641 (1997).

P. Pantano and D.R. Walt,* Toward a Near-Field Optical Array, Review of Scientific Instrumentation 68, 1357-1359 (1997).

S. Arbault, P. Pantano, N. Sojic, C. Amatore, M. Best-Belpomme, A. Sarasin and M. Vuillaume,* Activation of the NADPH Oxidase in Human Fibroblasts by Mechanical Intrustion of a Single Cell with an Ultramicroelectrode, Carcinogenesis 18, 569-574 (1997).

P. Pantano and D.R. Walt,* Ordered Nanowell Arrays, Chemistry of Materials 8, 2832-2835 (1996).

P. Pantano and D.R. Walt,* Analytical Applications of Optical Imaging Fibers, Analytical Chemistry 67, 481A-487A (1995).

K.S. Bronk, K.L. Michael, P. Pantano and D.R. Walt,* Combined Imaging and Chemical Sensing Using a Single Optical Imaging Fiber, Analytical Chemistry 67, 2750-2757 (1995).

S. Arbault, P. Pantano, J.A. Jankowski, M. Vuillaume and C. Amatore,* Monitoring an Oxidative Stress Mechanism at a Single Human Fibroblast, Analytical Chemistry 67, 3382-3390 (1995).

P. Pantano and W.G. Kuhr,* Enzyme-Modified Microelectrodes for In Vivo Neurochemical Measurements, Electroanalysis 7, 405-416 (1995).

P. Pantano and W.G. Kuhr,* Characterization of the Chemical Architecture of Carbon-Fiber Microelectrodes, Part 2: Correlation of Carboxylate Distribution with Electron Transfer Properties, Analytical Chemistry 65, 2452-2458 (1993).

P. Pantano and W.G. Kuhr,* Dehydrogenase-Modified Carbon-Fiber Microelectrodes for the Measurement of Neurotransmitter Dynamics, Part 2: Covalent Modification Utilizing Avidin-Biotin Technology, Analytical Chemistry 65, 623-630 (1993).

W.G. Kuhr,* V.L. Barrett, M.R. Gagnon, P. Hopper and P. Pantano, Dehydrogenase-Modified Carbon-Fiber Microelectrodes for the Measurement of Neurotransmitter Dynamics, Part 1: NADH Voltammetry, Analytical Chemistry 65, 617-622 (1993).

P. Pantano and W.G. Kuhr,* Characterization of the Chemical Architecture of Carbon-Fiber Microelectrodes, Part 1: Carboxylates, Analytical Chemistry 63, 1413-1418 (1991).

P. Pantano, T.H. Morton and W.G. Kuhr,* Enzyme-Modified Carbon-Fiber Microelectrodes with Millisecond Response Times, Journal of the American Chemical Society 113, 1832-1833 (1991).

P. Pantano and J. Sneddon,* Effect of Atomization Surface on the Quantitation of Vanadium by Electrothermal Atomization Atomic Absorption Spectrometry, Applied Spectroscopy 43, 504-510 (1989).


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