research

My interests lie in using cutting-edge machine learning approaches for modelling regulatory processes (from transcriptional through post-translational) encoded in the genome and epigenome, understanding how these processes evolve using theoretical models of sequence evolution and natural selection, and understanding the impact of such regulatory evolution on function, disease and treatment, and their interplay.

I presently focus on molecular mechanisms in sensory neurons, working on their transcriptional and translational regulatory programs, and whether they are conserved between mammalian model systems and humans. I work as part of the multidisciplinary Pain Neurobiology Research Group leading computational neurogenomics projects, and work closely with Theodore Price. I also work closely with Gregory Dussor, and Patrick Dougherty.

At UT Dallas, I have previously worked with the NIH Roadmap Epigenome Consortium on epigenetic regulation and transcriptomics of pluripotent cells, neural progenitors and neurons.

For details, see the Pain Neurobiology lab website, projects and publications.

Projects

Publications

Press