Chem 3321 -- Physical Chemistry I
Syllabus
TA (Aidely Aranda) web page:
TA (Aidely Aranda) web pageChem3321 Lecture Notes
Chem3321math1.pdf Math rules for Derivative manipulations.Chem3321chapter16.pdf Chapter 16. Gases and real gases.
Chem3321chapter19.pdf Chapter 19. First Law; enthalpy
Chem3321chapter20.pdf Chapter 20. Second Law.
Chem3321chapter21.pdf Chapter 21. Third Law.
Chem3321chapter22.pdf Chapter 22. Free Energy.
Ch22_GTS.pdf Chapter 22 extra detail.
Chem3321chapter26.pdf Chapter 26. Equilibrium Constant.
Torabifard_March6_2023.pdf March 6 lecture by Dr. Torabifard
Torabifard_March8_2023.pdf March 8 lecture by Dr. Torabifard
Chem3321chapter23.pdf Chapter 23. Phase Equilibria.
Chem3321chapter24.pdf Chapter 24. Liquid-Liquid solutions.
Chem3321chapter25.pdf Chapter 25. Solid-Liquid solutions.
Chem3321chapter27.pdf Chapter 27. Kinetic Theory of Gases.
Chem3321chapter28.pdf Chapter 28. Rate Laws.
Chem3321chapter29.pdf Chapter 29. Reaction Mechanisms.
Chem3321chapter31.pdf Chapter 31. Chemsorption.
HOMEWORK / TESTS
Homework #1, due January 23Homework #1 solutions
Homework #2, due January 30
Homework #2 solutions
Homework #3, due February 6
Homework #3 solutions
Homework #4, due February 20
Homework #4 solutions
Test #1 practice
Test #1 solutions
Homework #5, due March 20
Homework #6, due March 27
EXTRA MATERIAL
(EC = Physical Chemistry with Applications to the Life Sciences by David Eisenberg and Donald Crothers)(KW = The Molecules of Life by John Kuriyan, Boyana Konforti, and David Wemmer)
(H = Thermodynamics and Kinetics for the Biological Sciences by Gordon G. Hammes)
coupled endergonic/exergonic reactions, page 196 EC
water and the hydrophobic effect
Figure 19.5 from the Simon/McQuarrie textbook
heat capacity of protein or DNA in water, page 258 KW
heat capacity of different CG lengths of DNA
entropy, coin toss, page 296 KW
entropy, deviation from most probable, page 309 KW
some standard free energies of formation, page 392 KW
formation free energy of glucose in terms of combustion reactions, page 394 KW
different kinds of work that can be done by a system, page 399 KW
kinesin motor protein work coupled to ATP hydrolysis, pge 403 KW
coupling of chemical work to ATP hydrolysis, page 403 KW
reaction quotient and ΔG of ATP hydrolysis, page 428 KW
Fig 10.12 from page 437 KW, His / Asp interaction
Fig 14.25 from page 659 KW, His / Asp interaction in hemoglobin
Fig 10.14 from KW, intra vs inter molecular hydrogen bonding
Fig 10.17 from KW, unfolded conformations assuming to be of equal probability
Figs 10.19 and 10.20 from KW, torsion/sidechain protein conformations
Figs 4.20 and 4.22 from KW, Ramachandran diagram for torsions
Figs 10.21 and 10.22 from KW, entropy of water near hydrophobic group
Fig 10.23 from KW, hydrophobic residues, folding, water
Fig 10.24 from KW, DSC schematic
Figs 10.25 and 10.28 from KW, heat capacity of protein unfolding
Table 10.3 from KW, thermodynamics of protein unfolding
Fig 24.2 from Simon and McQuarrie: definition of ideal solution
Fig 5.60 from Atkins: illustration of non-ideal behavior of ionic solutions
March 3 ITC lecture by Ke Ji
G-binding domain 1 of Streptococcal Protein G
plot of protein stability vs. temperature for the protein G-B1
cold unfolding paper, Biophys. Chem. 208, 4-8 (2016)
Fig 12.13 from KW, inhibitor vs. ATP in protein kinase binding pocket
Fig 12.14 from KW, development of imatinib by optimization of lead compounds
Fig 12.21 from KW, lock-and-key vs. induced fit models for protein-ligand binding
Fig 12.22 from KW, ligand binding through conformational selection
Fig 12.24 from KW, affinity vs. specificity of imatinib and dasatinib
Textbook Chapters 24 and 25
Chapter24textbook.pdf Textbook Chapter 24.Chapter25textbook.pdf Textbook Chapter 25.
Chem3321 mp4 Video Recordings from a few years ago
General introductionChapter 16 part 1
Chapter 16 part 2
Chapter 16 part 3
Chapter 16 part 4
Chapter 16 part 5
Chapter 16 part 6
Chapter 16 part 7
Chapter 19 part 1
Chapter 19 part 2
Chapter 19 part 3
Chapter 19 part 4
Chapter 19 part 5
Chapter 19 part 6
Chapter 19 part 7
Chapter 19 part 8
Chapter 19 part 9
Chapter 19 part 10
Chapter 19 part 11
Chapter 19 part 12
Chapter 19 part 13
Chapter 19 part 14
Chapter 20 part 1
Chapter 20 part 2
Chapter 20 part 3
Chapter 20 part 4
Chapter 20 part 5
Chapter 20 part 6
Chapter 20 part 7
Chapter 20 part 8
Chapter 20 part 9
Chapter 20 part 10
Chapter 20 part 11
Chapter 20 part 12
Chapter 20 part 13
Chapter 20 part 14
Chapter 20 part 15
Chapter 20 part 16
Chapter 21 part 1
Chapter 21 part 2
Chapter 22 part 1
Chapter 22 part 2
Chapter 22 part 3
Chapter 22 part 4
Chapter 22 part 5
Chapter 22 part 6
Chapter 22 part 7
Chapter 22 part 8
Chapter 22 part 9
Chapter 22 part 10
Chapter 22 part 11
Chapter 22 part 12
Chapter 26 part 1
Chapter 26 part 2
Chapter 26 part 3
Chapter 26 part 4
Chapter 26 part 5
Chapter 26 part 6
Chapter 26 part 7
Chapter 26 part 8
Chapter 26 part 9
Chapter 26 part 10
Chapter 26 part 11
Chapter 26 part 12
Chapter 26 part 13
Chapter 26 part 14
Chapter 26 part 15
Chapter 26 part 16
Chapter 26 part 17
Chapter 26 part 18
Chapter 26 part 19
Chapter 23 part 1
Chapter 23 part 2
Chapter 23 part 3
Chapter 23 part 4
Chapter 23 part 5
Chapter 23 part 6
Chapter 24 part 1
Chapter 24 part 2
Chapter 24 part 3
Chapter 24 part 4
Chapter 24 part 5
Chapter 24 part 6
Chapter 24 part 7
Chapter 25 part 1
Chapter 25 part 2
Chapter 25 part 3
Chapter 27 part 1
Chapter 27 part 2
Chapter 27 part 3
Chapter 27 part 4
Chapter 27 part 5
Chapter 27 part 6
Chapter 27 part 7
Chapter 27 part 8
Chapter 27 part 9
Chapter 27 part 10
Chapter 27 part 11
Chapter 27 part 12
Chapter 27 part 13
Chapter 28 part 1
Chapter 28 part 2
Chapter 28 part 3
Chapter 28 part 4
Chapter 28 part 5
Chapter 28 part 6
Chapter 28 part 7
Chapter 28 part 8
Chapter 28 part 9
Chapter 28 part 10
Chapter 28 part 11
Chapter 28 part 12
Chapter 29 part 1
Chapter 29 part 2
Chapter 29 part 3
Chapter 29 part 4
Chapter 29 part 5
Chapter 29 part 6
Chapter 29 part 7
Chapter 29 part 8
Chapter 31 part 1
Chapter 31 part 2
Chapter 31 part 3
Chapter 31 part 4
Chapter 31 part 5
Chapter 31 part 6
Chapter 31 part 7
Chapter 31 part 8
Chapter 31 part 9
NONGRADED HOMEWORK
Chapter 16:
9,10,19,22,35,38,58,59 Chapter 16 solutions
Chapter 19: 4,5,9,15,19,21,22,25,27,29,30,35,40,44,52
Chapter 19 solutions
Chapter 20: 6,8,13,14,18,25,26,27,29,31,32
Chapter 20 solutions
Chapter 21: 1,3,10,14
Chapter 21 solutions
Chapter 22: 1,5,8,9,11,12,17,18,19,23,24
Chapter 22 solutions
Chapter 26: 1,3,6,7,8,10,12,15,21,23,24,31,58,61,63,64,65
Chapter 26 solutions
Chapter 23: 1,4,6,20,21,22,27,28,29,33,36
Chapter 23 solutions
Chapter 24: 14,15,16,17,20,32,48,49,50,51
Chapter 24 solutions
Chapter 25: 1,4,5,15,16,24,27,28,29,30,31,32,37,40,41,42
Chapter 25 solutions
Chapter 27: 3,6,12,21,24,26,32,35,36,39,42,47,49,51,52
Chapter 27 solutions
Chapter 28: 2,7,8,9,12,14,17,19,20,26,33,34,38,41,42,43
Chapter 28 solutions
Chapter 29: 2,7,9,10,16,17,20,21,23,31,34,35,36,40
Chapter 29 solutions
Chapter 31: Chapter 31 solutions