Receptor binding

2_06
A woking model for receptor-mediated response. Effects of drugs on the relative concentrations of two hypothetical forms of a receptor, Ra (active) and Ri (inactive) that are in equilibrium. The relative distribution of the receptor between these two forms is differentially influenced by the agonists (A), partial agoinsts (P), competitive antagonists (C), and negative antagonists (N), also known as inverse agonists.