Receptor binding

2_21
Simple ternary complex model. The receptor ligand complex C1 may bind with an accessory component X to form a ternary complex C3. Alternatively, the free receptor/effector binary complex C2 may bind with a ligand molecule L to form the ternary complex.

Fig 2-23

Receptor dimerization model. Ligand binding and dissociation steps are described by the rate constants kf, kf1, kf2, kr, kr1, kr2. Free receptor/free receptor coupling, complex/free receptor coupling, and complex/complex coupling are described by the rate constants kc, kc1, kc2, ku, ku1, and ku2.