Intracellular hormone receptors

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Processing of ACTH synthesis and the sequence of ACTH. A schematic overview of the pathway by which proopiomelanocortin (POMC) is converted to ACTH and other peptides in the anterior pituitary is shown. The light blue boxes behind the ACTH structure indicate regions identified as important for steroidogenic activity (residues 6-10) and binding to the ACTH receptor (15-18). The amino acid sequence of human ACTH is shown. LPH, lipotropin; MSH, melanocyte-stimulating hormone.